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Background To ensure reliability of additively manufactured components in structural applications, an understanding of the combined behavior of pores and stress state on failure behavior is required. Objective This research aims to identify the capabilities and limitations of stress- and strain-based fracture models in describing failure in complex additively manufactured structures. Methods SS316L brackets with a three-dimensional truss-based geometry, in which stress state and pore size varied among struts, were fabricated with laser powder bed fusion. Fracture models considering both stress state and pore size, formulated in terms of stress (pore-size dependent Mohr–Coulomb, or P-MC) and strain (pore-size dependent Modified Mohr–Coulomb, or P-MMC), were calibrated and used to predict the fracture behavior of the brackets. Results The P-MMC fracture model correctly predicted the experimentally observed fracture locations for 11 out of 12 samples, while the P-MC fracture model correctly predicted 10 out of 12 samples. Below a critical pore size, stress state effects dominated the fracture behavior, and above this, pore size was the critical factor, where capturing both factors was crucial at intermediate pore sizes. Conclusions The P-MC fracture model was appropriate for predicting the maximum load-bearing capacity for all samples in this study, while the P-MMC fracture model was shown to be only applicable for samples containing small pores. The importance of incorporating both stress state and the presence of pores in a fracture model is necessary to ensure confidence in the load carrying capacity of additively manufactured structures.